diff --git a/mm/damon/reclaim.c b/mm/damon/reclaim.c
index 7126d47fb8b2..ed446d00ef1c 100644
--- a/mm/damon/reclaim.c
+++ b/mm/damon/reclaim.c
@@ -210,6 +210,11 @@ static int damon_reclaim_apply_parameters(void)
 	param_ctx->addr_unit = addr_unit;
 	param_ctx->min_region_sz = max(DAMON_MIN_REGION_SZ / addr_unit, 1);
 
+	if (!is_power_of_2(param_ctx->min_region_sz)) {
+		err = -EINVAL;
+		goto out;
+	}
+
 	if (!damon_reclaim_mon_attrs.aggr_interval) {
 		err = -EINVAL;
 		goto out;