diff --git a/drivers/pmdomain/imx/imx8m-blk-ctrl.c b/drivers/pmdomain/imx/imx8m-blk-ctrl.c
index fe083b1e7251..14fb969bba28 100644
--- a/drivers/pmdomain/imx/imx8m-blk-ctrl.c
+++ b/drivers/pmdomain/imx/imx8m-blk-ctrl.c
@@ -15,6 +15,7 @@
 #include <linux/pm_runtime.h>
 #include <linux/regmap.h>
 #include <linux/clk.h>
+#include <linux/mutex.h>
 
 #include <dt-bindings/power/imx8mm-power.h>
 #include <dt-bindings/power/imx8mn-power.h>
@@ -34,6 +35,12 @@ struct imx8m_blk_ctrl {
 	struct regmap *regmap;
 	struct imx8m_blk_ctrl_domain *domains;
 	struct genpd_onecell_data onecell_data;
+	/*
+	 * Serializes the blk-ctrl reset/clock sequence across sibling domains;
+	 * their transitions interact through the shared VPUMIX bus domain,
+	 * VPU_NOC and the not-ack-verified ADB400 handshake (ERR050531).
+	 */
+	struct mutex power_lock;
 };
 
 struct imx8m_blk_ctrl_domain_data {
@@ -98,6 +105,8 @@ static int imx8m_blk_ctrl_power_on(struct generic_pm_domain *genpd)
 	struct imx8m_blk_ctrl *bc = domain->bc;
 	int ret;
 
+	guard(mutex)(&bc->power_lock);
+
 	/* make sure bus domain is awake */
 	ret = pm_runtime_resume_and_get(bc->bus_power_dev);
 	if (ret < 0) {
@@ -163,6 +172,8 @@ static int imx8m_blk_ctrl_power_off(struct generic_pm_domain *genpd)
 	const struct imx8m_blk_ctrl_domain_data *data = domain->data;
 	struct imx8m_blk_ctrl *bc = domain->bc;
 
+	guard(mutex)(&bc->power_lock);
+
 	/* put devices into reset and disable clocks */
 	if (data->mipi_phy_rst_mask)
 		regmap_clear_bits(bc->regmap, BLK_MIPI_RESET_DIV, data->mipi_phy_rst_mask);
@@ -201,6 +212,10 @@ static int imx8m_blk_ctrl_probe(struct platform_device *pdev)
 
 	bc->dev = dev;
 
+	ret = devm_mutex_init(dev, &bc->power_lock);
+	if (ret)
+		return ret;
+
 	bc_data = of_device_get_match_data(dev);
 
 	base = devm_platform_ioremap_resource(pdev, 0);