diff --git a/arch/s390/include/asm/cpacf.h b/arch/s390/include/asm/cpacf.h
index a83683169d98..6174552d856d 100644
--- a/arch/s390/include/asm/cpacf.h
+++ b/arch/s390/include/asm/cpacf.h
@@ -301,6 +301,7 @@ static __always_inline void __cpacf_query(unsigned int opcode,
 					  cpacf_mask_t *mask)
 {
 	__cpacf_query_insn(opcode, mask, CPACF_FC_QUERY);
+	kmsan_unpoison_memory(mask, sizeof(*mask));
 }
 
 static __always_inline int __cpacf_check_opcode(unsigned int opcode)
@@ -370,6 +371,7 @@ static __always_inline int cpacf_query_func(unsigned int opcode,
 static __always_inline void __cpacf_qai(unsigned int opcode, cpacf_qai_t *qai)
 {
 	__cpacf_query_insn(opcode, qai, CPACF_FC_QUERY_AUTH_INFO);
+	kmsan_unpoison_memory(qai, sizeof(*qai));
 }
 
 /**
@@ -422,6 +424,7 @@ static inline int cpacf_km(unsigned long func, void *param,
 		  [opc] "i" (CPACF_KM)
 		: "cc", "memory", "0", "1");
 
+	kmsan_unpoison_memory(dest, src_len - s.odd);
 	return src_len - s.odd;
 }
 
@@ -454,6 +457,7 @@ static inline int cpacf_kmc(unsigned long func, void *param,
 		  [opc] "i" (CPACF_KMC)
 		: "cc", "memory", "0", "1");
 
+	kmsan_unpoison_memory(dest, src_len - s.odd);
 	return src_len - s.odd;
 }
 
@@ -587,6 +591,7 @@ static inline int cpacf_kmctr(unsigned long func, void *param, u8 *dest,
 		  [opc] "i" (CPACF_KMCTR)
 		: "cc", "memory", "0", "1");
 
+	kmsan_unpoison_memory(dest, src_len - s.odd);
 	return src_len - s.odd;
 }
 
@@ -619,6 +624,7 @@ static inline void cpacf_prno(unsigned long func, void *param,
 		: [fc] "d" (func), [pba] "d" ((unsigned long)param),
 		  [seed] "d" (s.pair), [opc] "i" (CPACF_PRNO)
 		: "cc", "memory", "0", "1");
+	kmsan_unpoison_memory(dest, dest_len);
 }
 
 /**