diff --git a/drivers/comedi/drivers/ni_atmio16d.c b/drivers/comedi/drivers/ni_atmio16d.c
index 6765cdc276ca..87fed16b112c 100644
--- a/drivers/comedi/drivers/ni_atmio16d.c
+++ b/drivers/comedi/drivers/ni_atmio16d.c
@@ -593,7 +593,9 @@ static int atmio16d_attach(struct comedi_device *dev,
 	/* reset the atmio16d hardware */
 	reset_atmio16d(dev);
 
-	if (it->options[1]) {
+	/* only irqs 3, 4, 5, 6, 7, 9, 10, 11, 12, 14, and 15 are valid */
+	if (it->options[1] >= 3 && it->options[1] <= 15 &&
+	    (1 << it->options[1]) & 0xdef8) {
 		ret = request_irq(it->options[1], atmio16d_interrupt, 0,
 				  dev->board_name, dev);
 		if (ret == 0)