diff --git a/drivers/iommu/amd/iommu.c b/drivers/iommu/amd/iommu.c
index f1333071da10..0c042668b32d 100644
--- a/drivers/iommu/amd/iommu.c
+++ b/drivers/iommu/amd/iommu.c
@@ -1770,7 +1770,8 @@ void amd_iommu_domain_flush_pages(struct protection_domain *domain,
 {
 	lockdep_assert_held(&domain->lock);
 
-	if (likely(!amd_iommu_np_cache)) {
+	if (likely(!amd_iommu_np_cache) ||
+		size >= (1ULL<<52)) {
 		__domain_flush_pages(domain, address, size);
 
 		/* Wait until IOMMU TLB and all device IOTLB flushes are complete */