diff --git a/tools/perf/builtin-c2c.c b/tools/perf/builtin-c2c.c
index 3dd45a550fdb..f060dfbe11c2 100644
--- a/tools/perf/builtin-c2c.c
+++ b/tools/perf/builtin-c2c.c
@@ -245,6 +245,10 @@ static void c2c_he__set_cpu(struct c2c_hist_entry *c2c_he,
 		      "WARNING: no sample cpu value"))
 		return;
 
+	/* cpuset bitmap has c2c.cpus_cnt bits from env->nr_cpus_avail */
+	if (sample->cpu >= (unsigned int)c2c.cpus_cnt)
+		return;
+
 	__set_bit(sample->cpu, c2c_he->cpuset);
 }
 
@@ -262,6 +266,10 @@ static void c2c_he__set_node(struct c2c_hist_entry *c2c_he,
 	if (WARN_ONCE(node < 0, "WARNING: failed to find node\n"))
 		return;
 
+	/* nodeset bitmap has c2c.nodes_cnt bits from env->nr_numa_nodes */
+	if (node >= c2c.nodes_cnt)
+		return;
+
 	__set_bit(node, c2c_he->nodeset);
 
 	if (c2c_he->paddr != sample->phys_addr) {
@@ -391,7 +399,12 @@ static int process_sample_event(const struct perf_tool *tool __maybe_unused,
 		 * Doing node stats only for single callchain data.
 		 */
 		int cpu = sample->cpu == (unsigned int) -1 ? 0 : sample->cpu;
-		int node = c2c.cpu2node[cpu];
+		int node;
+
+		/* cpu2node[] has c2c.cpus_cnt entries; large u32 wraps signed negative */
+		if (cpu < 0 || cpu >= c2c.cpus_cnt)
+			cpu = 0;
+		node = c2c.cpu2node[cpu];
 
 		c2c_hists = he__get_c2c_hists(he, c2c.cl_sort, 2, machine->env);
 		if (!c2c_hists) {
@@ -410,7 +423,9 @@ static int process_sample_event(const struct perf_tool *tool __maybe_unused,
 		c2c_he = container_of(he, struct c2c_hist_entry, he);
 		c2c_add_stats(&c2c_he->stats, &stats);
 		c2c_add_stats(&c2c_hists->stats, &stats);
-		c2c_add_stats(&c2c_he->node_stats[node], &stats);
+		/* node_stats[] has c2c.nodes_cnt entries */
+		if (node >= 0 && node < c2c.nodes_cnt)
+			c2c_add_stats(&c2c_he->node_stats[node], &stats);
 
 		compute_stats(c2c_he, &stats, sample->weight);